Placental Tissue-based HCT/P Products
 In the previous post, I began a review of a marketing blurb sent to my boss, Dr. David Karli, extolling the virtues of an amniotic fluid-containing product. I am sure you are wondering why I haven’t mentioned the name of the manufacturer and the offending product, but see the explanation provided in the previous post....
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Amniotic-derived Product False Claim
During a course offered by ASIPP last March in Las Vegas, NV, I gave a brief impromptu presentation about regulatory issues in the field of translational regenerative medicine. I mentioned that producers of placental tissue-derived products, like amniotic fluid products or amniotic fluid plus micronized amniotic tissue products, were sprouting like weeds, despite the issuing...
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SVF Preparation
In the previous post, I covered a material I call Fuzz Balls produced in the Lipogems System. My contention is that the Fuzz Balls can’t be used to treat orthopedic pathologies for regulatory reasons, which definitely is a minority position. I also mentioned that I had been taken to task for the somewhat tongue-in-cheek use...
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Lipogems Adipose Tissue
The previous post provided an introduction into what’s happening in the world of fat tissue-based therapeutic preparations in the USA. I focused on the situation in which physicians use enzymatic digestion of a patient’s fat tissue to manufacture stromal vascular fraction (SVF), which is a single cell suspension containing mesenchymal stem cells (MSCs). I ended the...
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Fat-derived SVF
While the use of adipose tissue for treating orthopedic pathologies currently is not compliant with regulations governing the manufacturing of HCT/Ps (human cells, tissues and cellular and tissue based products) in the USA, there are a lot of clinics out there, some of whom should know better, who are offering a variety of adipose tissue-derived...
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BMC as Alternative for TKA
I disposed in the previous post of the notion that you lose all of your bone marrow-based MSCs if you are elderly. That conclusion is based on one of Dr. Philippe Hernigou’s presentations during the recent national ASIPP conference. Dr. Hernigou is the pioneering physician who has been working with bone marrow concentrate (BMC) for treating...
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Bone Marrow and MSCs Through the Ages
There are a lot of folks going around saying that you suffer a dramatic loss of bone marrow stem cells (the mesenchymal stem cell [MSC] version) from your body’s bone marrow depots as you age. Which is true to a certain extent, but, as usual, the devil is in the details. Some of those who...
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