I disposed in the previous post of the notion that you lose all of your bone marrow-based MSCs if you are elderly. That conclusion is based on one of Dr. Philippe Hernigou’s presentations during the recent national ASIPP conference. Dr. Hernigou is the pioneering physician who has been working with bone marrow concentrate (BMC) for treating...Read More
There are a lot of folks going around saying that you suffer a dramatic loss of bone marrow stem cells (the mesenchymal stem cell [MSC] version) from your body’s bone marrow depots as you age. Which is true to a certain extent, but, as usual, the devil is in the details. Some of those who...Read More
In the previous post, I reviewed results reported by Dr. Philippe Hernigou about the significant loss of MSCs and satellite cells (the stem cell in the muscles) from the tissue of patients who had received a certain kind of implant liner in their primary total hip replacement. The publication showed that patients with the largest...Read More
One of the important lessons embedded in the clinical results Dr. Philippe Hernigou has published in a dozen or so papers on the benefits of using bone marrow concentrate (BMC) in treating orthopedic pathologies is that having a healthy bone marrow depot close to the site of pathology will aid in restoring/repairing the orthopedic injury....Read More
One theme of the last few posts on Dr. Philippe Hernigou’s pioneering use of BMC to treat soft and bony tissue pathologies has been the need to boost the bone marrow cellularity and/or its vitality. What? You haven’t caught on that the real objective of treating orthopedic pathologies is to make sure the adjacent bone...Read More
In the last post,I reviewed the therapeutic benefit reported by Dr. Philippe Hernigou for using BMC to treat ankle non-unions in diabetic patients. I will move on in this post to cover Dr. Hernigou’s use of BMC in another bony pathology, namely avascular necrosis of the femoral head, also referred to as osteonecrosis of the...Read More
In the last post, I reviewed the potent anti-microbial benefits of bone marrow concentrate (BMC) published in a paper by Dr. Philippe Hernigou in treating antibiotic-refectory infections in non-unions. I will move on in this post to cover Dr. Hernigou’s use of BMC in treating non-unions of the foot and ankle in diabetic patients. I...Read More
Continuing in my effort to review Dr. Philippe Hernigou’s publications on the use of bone marrow concentrate (BMC) in treating a variety of orthopedic pathologies, I would like to cover a very recent publication in which he presents clinical data supporting the use of BMC as a means of eliminating microbial infections in fracture sites....Read More
In the last post, I focused solely on adverse events associated with the bone marrow aspiration (BMA) procedure itself. In this post, I would like to return to another of Dr. Hernigou’s classic publications on the use of BMC to treat long-bone non-unions. I covered his publication on the benefits of BMC-augmentation of a surgical...Read More
As I reviewed the first clinical paper in my series highlighting the advantages of using bone marrow concentrate (BMC) in treating orthopedic pathologies (Part One and Part Two), I tried to fulfill my promise to the FDA to point out adverse events reported in the publication. However, I realized that by and large the adverse...Read More
